MMG 240 2014 Structural Biology Wiki
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Overall Structure[]

P53 structure

Cartoon representation of the p53 tetramer complexed with dsDNA.












Surface[]

P53 surface

p53 tetramer displaying an electrostatic surface. Blue indicates positive charge, red indicates negative charge.












Unique Feature - Zinc Finger[]

Zn finger 4

Zinc finger clusters in p53.










Zn finger 5

Zoomed view of a single Zinc finger in p53. Histidine residues shown in red, Cysteine residues shown in blue, Zinc molecule shown in green.












Homology - Mus musculus (mouse)[]

Homolog 2

Structural superimposition of human p53 and the DNA-binding domain found in Mus musculus p53. RMS = 0.257 (144 to 144 atoms)

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